BDBM50380144 CHEMBL2010994::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 8
SMILES CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(cc2)S(N)(=O)=O)n1
InChI Key InChIKey=OMYTZYUGUKDESE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50380144
Affinity DataKoff: 1.10E+6s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 4.00E+5s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 5.70E+4s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0250M-1s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0710M-1s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMpH: 6.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 6 by surface p...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+3nMpH: 6.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 6 by surface pl...More data for this Ligand-Target Pair
Affinity DataKon: 0.0560M-1s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 230nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface p...More data for this Ligand-Target Pair
Affinity DataKd: 260nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 7 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 71nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.0490M-1s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 44nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface p...More data for this Ligand-Target Pair
Affinity DataKd: 82nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 0.0280nMAssay Description:Binding affinity to CA12 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.00250M-1s-1Assay Description:Binding affinity to CA12 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 143nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 12 by thermal shift assayMore data for this Ligand-Target Pair